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Topic: Research

1. Fact Sheet: Report on the 4th International Symposium on Functional Gastrointestinal Disorders

   125

   By: Douglas A. Drossman, MD; William F. Norton, Communications Director, IFFGD

   There is a growing understanding of the multi-faceted nature of functional gastrointestinal disorders. Symptoms, behaviors, and treatment outcomes for individuals with these disorders relate to disturbances in gastrointestinal motility and sensation that is effected by interactions that take place via the brain-gut axis. To understand and study these conditions, physicians and researchers must become familiar with evolving knowledge that integrates basic science, physiology, clinical medicine, psychology, and psychiatry. Indicated below are some of the highlights of the presentations at the 4th International Symposium for Functional Gastrointestinal Disorders, which we believe truly reflect the developing areas of research in irritable bowel syndrome (IBS) and the functional gastrointestinal (GI) disorders.

   Topics: IFFGD, General Interest, Research
   Non-Member Price: FREE

2. Fact Sheet: Report on the 5th International Symposium on Functional Gastrointestinal Disorders

   177

   By: Douglas A. Drossman, MD; William F. Norton, Communications Director, IFFGD

   Our understanding of the functional GI disorders is changing, including the mechanisms that contribute to symptom generation, methods of assessing and diagnosing the disorders, and approaches to treatment. As indicated by data presented across multiple disciplines at this symposium - basic, mechanistic, physiological, clinical, and epidemiological - the clinical expression of the functional GI disorders includes a composite of several physiological components. In effect, there is no one factor that appears to be involved in the development of the disorders (etiology), nor is there one specific treatment.

   Topics: IFFGD, General Interest, Research
   Non-Member Price: FREE

3. Fact Sheet: Report on the 6th International Symposium on Functional Gastrointestinal Disorders

   199

   By: Douglas A. Drossman, MD; William F. Norton, Communications Director, IFFGD

   A summary of presentations from over 80 experts that address the way research and science are improving our understanding of functional GI disorders, and the new avenues being investigated. Topics are covered such as, who is more likely to get a functional GI disorder, how do brain-gut interactions influence symptoms, diagnosis and treatment approaches, and what's new on the treatment horizon.

   Topics: IFFGD, General Interest, Research
   Non-Member Price: FREE

4. Fact Sheet: Report from IFFGD Research Award Winner: Understanding Pain and Discomfort in Functional GI Disorders

   203

   By: Klaus Bielefeldt, MD, PhD

   Pain, a burning or otherwise uncomfortable sensation in the upper abdomen, nausea, or fullness - all of these are symptoms many patients list when they seek medical advice. While we may think of ulcers, gallstones or perhaps inflammation of the pancreas as the cause, all too often even extensive and sophisticated testing does not show any abnormalities. So, why do all these persons feel pain or any of the other symptoms they report?

   Topics: Dyspepsia, pain in upper abdomen or chest, Inflammation, Lower Abdominal Pain, Pelvic Pain, Pain Management, Research
   Non-Member Price: FREE

5. Fact Sheet: Report from IFFGD Research Award Winner: Stress and Irritable Bowel Syndrome: Unraveling the Code

   211

   By: Yvette Tache, PhD

   Report from IFFGD Research Award Winner – Some common medical conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), fibromyalgia, and migraine headaches may be stress-related. Understanding of the mind and body's responses called upon during stress may provide insight on the underlying cause of IBS and open the door to new and more effective treatment. "Stress" is a term doctors use to describe normal responses in the body that are needed for health and survival. Our bodies regularly respond to the constant flow of changes that happen around and within us. CRF is the brain's "stress hormone." When stimulated, it interacts with many systems within the body. These interactions include those between the brain and the digestive tract. They effect whether or not we feel discomfort or pain, and the way our bowels move. In some people, the stress response is overactive. When the stress response is out of balance, unwanted symptoms can result.

    

   Topics: Brain-Gut, Irritable Bowel Syndrome (IBS), Research, Stress
   Non-Member Price: FREE

6. Fact Sheet: Report from IFFGD Research Award Winner: Understanding Intestinal Gas

   214

   By: Fernando Azpiroz, MD, PhD

   Everybody has gas in his or her digestive tract (the esophagus, stomach, small intestine/bowel, and large intestine/bowel). What is happening that causes painful or uncomfortable symptoms associated with gas in some persons while not in others? Report from this 2005 IFFGD Research Award Winner.

   Topics: Bacteria, gut flora, Diet, Foods, Gas, Bloating, Belching, Irritable Bowel Syndrome (IBS), Research
   Non-Member Price: FREE

7. Fact Sheet: Report on the 7th International Symposium for Functional Gastrointestinal Disorders

   222

   By: William F. Norton, Communications Director, IFFGD; Douglas A. Drossman, MD

   The 7^th International Symposium on Functional Gastrointestinal Disorders was held in Milwaukee on April 12–15, 2007. The meeting was sponsored by the University of Wisconsin School of Medicine and the International Foundation for Functional Gastrointestinal Disorders (IFFGD), in cooperation with the Functional Brain Gut Group (FBG). 

   This report highlights just some of the information presented at the Symposium. Nevertheless the information herein identifies several of the newer and more important research emerging in the field. Clearly many pieces of the puzzle are emerging, which will benefit patients with functional gastrointestinal (GI) and motility disorders. 

   Topics: IFFGD, General Interest, Research
   Non-Member Price: FREE

8. Fact Sheet: Report from IFFGD Research Award Winner: Role of the Central Immune System in Functional Disorders

   225

   By: Sylvie Bradesi, PhD

   A new concept of activation of immune cells within the central nervous system (CNS), including the brain and the spinal cord, has been proposed as a major factor contributing to the generation and maintenance of chronic pain.

   Topics: Brain-Gut, Irritable Bowel Syndrome (IBS), Pain Management, Research, Stress
   Non-Member Price: FREE

9. Fact Sheet: Report from IFFGD Research Award Winner: Irritable Bowel Syndrome: Searching for Underlying Causes

   229

   By: Magnus Simren, MD, PhD

   Dr. Simrén is a 2007 IFFGD Research Award recipient. His main research areas are the causes and development of functional GI disorders. In this article, Dr. Simrén discusses his research into the role of food and nutrients for gut function in IBS, and the link between different alterations of function and the symptom pattern of the patient.

   Topics: Bacteria, gut flora, Diet, Foods, Irritable Bowel Syndrome (IBS), Research
   Non-Member Price: FREE

10. Fact Sheet: Report from IFFGD Research Award Winner: Symptom Based Psychology for Functional Gastrointestinal Disorders

    230

    By: Bruce D. Naliboff, PhD

    How do we understand the many studies that show an increase in negative moods like anxiety or depression in those suffering from functional gastrointestinal (GI) and pain conditions? Are these psychological factors an important cause for the development and/or maintenance of symptoms in irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and other functional GI disorders? Or are they a result of maybe years of disrupted life activities and frequent periods of intolerable symptoms? 

    Topics: Brain-Gut, Irritable Bowel Syndrome (IBS), relaxation, Research, Working with your healthcare provider
    Non-Member Price: FREE