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Topic: Brain-Gut

  1. Brochure, Fact Sheet: The Neurobiology Basis of Mind Body Medicine


    By: Emeran A. Mayer, MD

    How do the mind and body interact with each other and the environment . . . and in this process actively maintain health and prevent disease? This accessable publication describes the basis for a growing awareness of an evolving convergence of many "alternative" concepts of health and disease with cutting edge concepts proposed by science. This is information that can be helpful to anyone with a chronic digestive disorder. A summary of a 1998 conference involving internationally recognized scientific leaders, and a group of prominent and unique practitioners of mind-body medicine.

    Also available offline as a 22 page soft-cover color booklet (8.5" x 11"). Contact IFFGD for details.

    Non-Member Price: $3.99 Add Item to Cart
  2. Fact Sheet: Irritable Bowel Syndrome: The Pathophysiologic Links to More Effective Future Therapy


    By: Michael Camilleri, MD

    Several investigators as well as an NIH consensus conference on the "irritable bowel syndrome" (IBS) have stressed the importance of the biopsychosocial model in the etiopathogenesis (origin and development) of this syndrome. In this short article, the pathophysiologic (disease process) links between big brain, little brain, motility and sensation are explored based on currently available data. These data suggest that investigators and clinicians need to be dissuaded from approaching IBS as though it was a single disorder in all patients, or as though only one mechanism is responsible for development of symptoms. In essence, this is a plea for the importance of integrated rather than reductionist approaches to research, diagnosis, and management of IBS. Revised and updated 2009.

    Non-Member Price: FREE View PDF
  3. Fact Sheet: Visceral Sensations and Brain-Gut Mechanisms


    By: Emeran A. Mayer, MD

    Over the past several years, different mechanisms located within the gut, or gut wall have been implicated as possible pathophysiologic mechanisms underlying the characteristic IBS symptoms of abdominal pain and discomfort. The list ranges from altered transit of intestinal gas, alterations in the colonic flora, immune cell activation in the gut mucosa, and alterations in serotonin containing enterochromaffin cells lining the gut. For those investigators with a good memory, these novel mechanisms can be added to an older list of proposed pathomechanisms, including altered gut motility ("spastic colitis") and alterations in mucus secretion.

    Non-Member Price: FREE View PDF
  4. Fact Sheet: Central Nervous System Modulation-Its Role in Irritable Bowel Syndrome


    By: Paul Enck, PhD

    Most of us have experienced some of the ways that the central nervous system (CNS) affects the gut in our everyday lives. The affect may be direct, like an urgent need to evacuate the bowels when life gets exciting. It may be indirect, like the decision to suppress the urge to go to the bathroom when social circumstances, work, or sanitary conditions do not allow it. In this article, we will examine four methods of brain-gut interaction and their influence on irritable bowel syndrome (IBS).

    Non-Member Price: FREE View PDF
  5. Fact Sheet: Using Relaxation in Coping with Gastrointestinal Disorders


    By: Kenneth R. Jones, PhD; Steve Heymen, MS

    Relaxation training is an integral component of behavioral therapies for managing chronic pain, promoting health, and helping patients cope with life-threatening illness. Relaxation can also assist in managing functional GI disorders. How relaxation works and methods are described. Reviewed 2009.

    Non-Member Price: FREE View PDF
  6. Fact Sheet: Hypnosis Treatment of Irritable Bowel Syndrome


    By: Olafur S. Palsson, PsyD

    The standard medical methods currently used to treat irritable bowel syndrome (IBS) are of some help to the majority of people with the disorder. However, up to half of IBS sufferers are dissatisfied with the results of standard medical management, and many continue to have frequent symptoms after seeing doctors about them. In recent years, other alternatives have been sought to help these individuals. There has been growing interest in the possibility of using the mind to soothe the symptoms of IBS. This article includes a description of hypnosis for IBS and how to select a hypnotherapist.

    Non-Member Price: FREE View PDF
  7. Fact Sheet: Hypnotherapy for Functional Gastrointestinal Disorders


    By: Peter J. Whorwell, MD

    Unfortunately, the word "hypnosis" often conjures up a whole variety of frequently quite negative connotations even within the medical profession. Many equate the phenomenon with the mind being taken over by the hypnotist and with loss of control by the recipient, which needless to say, is completely erroneous. As a consequence of this, the whole subject is surrounded by a cloud of mystery, which regrettably is often encouraged by those who practice the technique. Reviewed 2009.

    Non-Member Price: FREE View PDF
  8. Fact Sheet: Report from IFFGD Research Award Winner: Stress and Irritable Bowel Syndrome: Unraveling the Code


    By: Yvette Tache, PhD

    Report from IFFGD Research Award Winner – Some common medical conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), fibromyalgia, and migraine headaches may be stress-related. Understanding of the mind and body's responses called upon during stress may provide insight on the underlying cause of IBS and open the door to new and more effective treatment. "Stress" is a term doctors use to describe normal responses in the body that are needed for health and survival. Our bodies regularly respond to the constant flow of changes that happen around and within us. CRF is the brain's "stress hormone." When stimulated, it interacts with many systems within the body. These interactions include those between the brain and the digestive tract. They effect whether or not we feel discomfort or pain, and the way our bowels move. In some people, the stress response is overactive. When the stress response is out of balance, unwanted symptoms can result.


    Non-Member Price: FREE View PDF
  9. Fact Sheet: Sex Differences in Abdominal Pain


    By: Elie D. Al-Chaer, MS, PhD, JD

    Experimental and clinical studies highlight the existence of sex-related differences in the perception of and responsiveness to painful stimuli. Sex-related differences in pain processing and responsiveness in general have been documented in experimental studies using animal models, and pain is experienced differently by men and women.  Sex-related differences have also emerged in the search for new IBS-specific medications.

    Non-Member Price: FREE View PDF
  10. Fact Sheet: Report from IFFGD Research Award Winner: Role of the Central Immune System in Functional Disorders


    By: Sylvie Bradesi, PhD

    A new concept of activation of immune cells within the central nervous system (CNS), including the brain and the spinal cord, has been proposed as a major factor contributing to the generation and maintenance of chronic pain.

    Non-Member Price: FREE View PDF
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