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Topic: Inflammation

  1. Fact Sheet: Clinical Features and Treatments of Inflammatory Bowel Disease (IBD) - An Update


    By: Barry W. Jaffin, MD; Vera Kandror Denmark, MD

    Nearly two million people are affected with IBD [e.g., Crohn's disease and ulcerative colitis] in the U.S. These inflammatory conditions are a group of several distinct disorders which probably explains the diversity of extent and activity of inflammation within the gastrointestinal (GI) tract. The age of onset is usually in the 20s and 30s, although there is a slight second peak in incidence in the 50s to 60s. Men and women are equally affected in IBD as opposed to IBS, which is female predominant. Revised and updated 2009.

    Non-Member Price: FREE View PDF
  2. Fact Sheet: Report from IFFGD Research Award Winner: Understanding Pain and Discomfort in Functional GI Disorders


    By: Klaus Bielefeldt, MD, PhD

    Pain, a burning or otherwise uncomfortable sensation in the upper abdomen, nausea, or fullness - all of these are symptoms many patients list when they seek medical advice. While we may think of ulcers, gallstones or perhaps inflammation of the pancreas as the cause, all too often even extensive and sophisticated testing does not show any abnormalities. So, why do all these persons feel pain or any of the other symptoms they report?

    Non-Member Price: FREE View PDF
  3. Fact Sheet: Gut Bacteria and Irritable Bowel Syndrome


    By: Eamonn M. M. Quigley, MD

    Does bacteria play a role in IBS? If so, is it helpful or harmful? What about antibiotics, or probiotics? Bacteria are present in the normal gut (intestines) and in large numbers the lower parts of the intestine. These "normal" bacteria have important functions in life. A variety of factors may disturb the mutually beneficial relationship between the gut bacteria and its host – and disease may result. The possibility that gut bacteria could have a role in irritable bowel syndrome (IBS) may surprise some; there is indeed, now quite substantial evidence to support the idea that disturbances in the bacteria that populate the intestine may have a role in at least some patients with IBS. This article looks at recent findings about possible influences of bacteria in IBS, which may be either negative or positive, and at various treatment approaches.

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  4. Fact Sheet: Post-infectious Irritable Bowel Syndrome: A Sub-Type of Irritable Bowel Syndrome


    By: Robin Spiller, MD

    Irritable bowel syndrome is one of the most common gastrointestinal (GI) disorders. Within this large group of people, there is a small subgroup whose symptoms begin suddenly. It happens after what appears to be a bout of infection in the GI tract (gastroenteritis). How often do persons who suffer bacterial gastroenteritis develop IBS? Who gets post-infectious IBS and what causes the disorder? How is it treated? A review of the topic is presented.

    Non-Member Price: FREE View PDF
  5. Fact Sheet: Understanding Functional GI Disorders


    By: International Foundation for Functional Gastrointestinal Disorders IFFGD

    Functional gastrointestinal (GI) disorders are a highly prevalent group of persistent and recurring conditions that can affect any part of the GI tract. They afflict millions of people of all ages, causing discomfort ranging from inconvenience to disability. Yet they remain largely hidden and misunderstood. This article explains the challenges of the conditions and the approaches to diagnoses and treatments.

    Non-Member Price: FREE View PDF
  6. Fact Sheet: Peptic Ulcer: A Twentieth Century Disease


    By: W. Grant Thompson, MD, FRCPC

    Diagnosis and treatment of peptic ulcers and H. pylori infection. Reviewed and updated 2009.


    Non-Member Price: FREE View PDF
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